Does basal cell carcinoma arise from a precursor lesion?
Wong SY, Harms PW, and Dlugosz AA. Journal of Investigative Dermatology. 2025. (review)
Hair follicle stem cells and the collapse of self-tolerance in alopecia: the interplay of barrier function, the microbiome, and immunity
Durgin JS and Wong SY. EMBO Molecular Medicine. 2025. (commentary)
Hair follicles modulate skin barrier function
Ford NC*, Benedeck RE*, Mattoon MT, Peterson JK, Mesler AL, Veniaminova NA, Gardon DJ, Tsai SY, Uchida Y, Wong SY. Cell Reports. 2024. (*equal)
Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury
Veniaminova NA*, Jia YY*, Hartigan AM, Huyge TJ, Tsai SY, Grachtchouk M, Nakagawa S, Dlugosz AA, Atwood SX**, Wong SY**. Cell Reports. 2023. (*equal, **co-corresponding)
Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease
Trieu KG, Tsai SY, Eberl M, Ju V, Ford NC, Doane OJ, Peterson JK, Veniaminova NA, Grachtchouk M, Harms PW, Swartling FJ, Dlugosz AA, Wong SY. Cell Reports. 2022.
Preparing the hair follicle canal for hair shaft emergence
Mesler AL, Benedeck RE, Wong SY. Experimental Dermatology. 2021.
Niche-specific factors dynamically regulate sebaceous gland stem cells in the skin
Veniaminova NA, Grachtchouk M, Doane OJ, Peterson JK, Quigley DA, Lull MV, Pyrozhenko DV, Nair RR, Patrick MT, Balmain A, Dlugosz AA, Tsoi LC, Wong SY. Developmental Cell. 2019.
Tumor architecture and notch signaling modulate drug response in basal cell carcinoma
Eberl M, Mangelberger D, Swanson JB, Verhaegen ME, Harms PW, Frohm M, Dlugosz AA, Wong SY. Cancer Cell. 2018.
Loss of Gata6 causes dilation of the hair follicle canal and sebaceous duct
Swanson JB, Vagnozzi AN, Veniaminova NA, Wong SY. Experimental Dermatology. 2018.
Hair follicle terminal differentiation is orchestrated by distinct early and late matrix progenitors
Mesler AL*, Veniaminova NA*, Lull MV, Wong SY. Cell Reports. 2017. (*equal)
Hair follicle and interfollicular epidermal stem cells make varying contributions to wound regeneration
Vagnozzi AN, Reiter JF, Wong SY. Cell Cycle. 2015.
Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches
Peterson SC, Eberl M, Vagnozzi AN, Belkadi A, Veniaminova NA, Verhaegen ME, Bichakjian CK, Ward NL, Dlugosz AA, Wong SY. Cell Stem Cell. 2015.
Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration
Veniaminova NA, Vagnozzi AN, Kopinke D, Do TT, Murtaugh LC, Maillard I, Dlugosz AA, Reiter JF, Wong SY. Development. 2013.
Wounding mobilizes hair follicle stem cells to form tumors
Wong SY, Reiter JF. Proceedings of the National Academy of Sciences USA. 2011.
Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis
Wong SY, Seol AD, So PL, Ermilov AN, Bichakjian CK, Epstein EH Jr, Dlugosz AA, Reiter JF. Nature Medicine. 2009.
The Wong Lab @ The University of Michigan 